If you get this on Windows 8 or above on any TacO version above 008.513r please send me a dxdiag log so I can narrow down the problem.This can happen if you have the transparency effects turned off in Windows 7, probably because you're using the classic theme for Windows.I can see the TacO icon and/or the Map Timer, but the rest of the screen is black and I can't play.
In this case running GW2 TacO in admin mode should fix the problem. You most likely have GW2 running in admin mode (either you started it from an application that already had admin mode, or for other reasons like running Reshade) and GW2 TacO not. In this case the mouse input won't get transmitted to the application with the higher privileges.